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Kimura disease is a rare form of chronic inflammatory disorder of East Asian males, involving subcutaneous tissue, predominantly in the head and neck region and frequently associated with regional lymphadenopathy and/or salivary gland involvement.
Consistent histologic features were follicular hyperplasia, eosinophilic infiltrates, and proliferation of postcapillary venules.
In cntrast, angiolymphoid hyperplasia with eosinophilia occurs in all races and is characterized by generally smaller and more superficial lesions. Eosinophilia is common to both conditions, which are of unknown origin.
唾液腺腫脹を伴うIgG4関連硬化性疾患に好酸球増多を伴うことがあるとした場合、木村病の鑑別診断にgG4関連疾患もあげる必要がある。
Idiopathic retroperitoneal fibrosisに用いる免疫抑制薬について
・Marcolongo et al. Immunosuppressive therapy for idiopathic retroperitoneal fibrosis: a retrospective analysis of 26 cases.
The American Journal of Medicine Volume 116, Issue 3, 1 February 2004, Pages 194-197 (イタリア）
・269 アレルギー学会2008
IgG4+MOLPS: Mikulicz病では、唾液腺腫脹が強い割に、乾燥症状はは軽度と、Ann Rheum Dis, Aug 2008; doi:10.1136/ard.2008.089169 に記載されている。
