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Drug Approved. Is Disease Real? By ALEX BERENSON
NY TIMES Published: January 14, 2008
・Lyrica (Pfizer's drug pregabalin which is already a seller for seizures and diabetic nerve damages; Approved by FDA for FM in 2007 June; In November, Pfizer began a television ad campaign for Lyrica) and two other drugs (= Eli Lilly's Cymbalta and Forest Laboratories' milnacipran, both of which were originally developed as antidepressants) that may be approved this year
・Controversial; ACR, FDA and insurers recognize FM as a diagnosable disease. But doctors who are skeptical of FM think that vague complaints of chronic pain do not add up to a disease
Feng H, Shuda M, Chang Y, Moore PS. Clonal Integration of a Polyomavirus (=the seventh virus linked to human cancers) in Human Merkel Cell Carcinoma. Science 2008
They detected a fusion transcript between a previously undescribed virus T antigen and a human receptor tyrosine phosphatase in 80% of MCC vs 8-16% of controls.
Drug Has No Benefit in Trial, Makers Say By ALEX BERENSON
NY TIMES Published: January 14, 2008
New Questions on Treating Cholesterol By ALEX BERENSON
NY TIMES Published: January 17, 2008
