・急性の一酸化炭素中毒は、ある程度診断がしやすいと思いますが、慢性的になると症状が非特異的で、診断がなかなか難しいと思われます。ＮＥＪＭに総説的な論文がありました。
Carbon Monoxide Poisoning
Lindell K. Weaver, M.D. A 39-year-old female executive has a several-month history of fatigue, headache, and memory lapse. Multiple specialists have performed evaluations, but no diagnosis has been established. During a period of feeling worse than usual, she called a friend, who arrived at the residence to find the woman semicomatose and called 911. The patient was given supplemental oxygen and transported to the emergency department, where she is alert and has nonfocal findings on examination. Her carboxyhemoglobin level is 18%. How should she be treated? What is the expected outcome?
あとは、本文をどうぞ。
http://content.nejm.org/cgi/content/full/360/12/1217
日常診療では、なんせ、症状が非特異的なので、この病気を疑わないとなかなか診断できないのではないかと思います。
