・珪酸が，強皮症にも関係ありますよといった記事を書こうと思って，UpToDateをみてみると，どうもcontroversialの様で，ちょっとガクッと来ましたが，risk factorとして以下のような記述がありました．
Petroleum-based products — A relationship between certain toxic exposures and SSc or scleroderma-like syndromes is fairly convincing. Examples include the following:
- Among 178 patients with SSc and 200 control individuals, men with the disorder had higher cumulative exposure to organic solvents than controls .
- Among 660 women with SSc and 2227 controls, exposure to paint removers and paint thinners, but not to trichloroethylene, was significantly more likely to have occurred in the SSc group .
- Among 93 French patients with SSc, exposure to cleaning products, solvents, and/or synthetic adhesives was associated with increased risk .
つまり，有機溶剤の類の使用は，強皮症のリスクがあると言うことです．
・膠原病を診るときは，職業歴が必須ですよね．
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