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Joint Bone Spine. 2002 Jan;69(1):68-71.
Costallat LT, De Capitani EM, Zambon L.
Department of Clinical Medicine, Faculty of Medical Sciences, State University of Campinas, São Paulo, Brazil.
We reporttwo cases of coexistence of pulmonary silicosis and systemic lupus erythematosus (SLE). The patients are two men with SLE exposed to silica for 20 years. The hypothesis that silica exposure is linked to a wide variety of known or suspected autoimmune diseases, including SLE, has been discussed in the last decade but few cases of pulmonary silicosis and SLE were reported. Our purpose was to bring attention to the increasing evidence that silica may also cause or stimulate SLE, and to suggest that the researchers look for occupational exposure, mainly in male SLE patients.
PMID: 11858360 [PubMed - indexed for MEDLINE]
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